Multigene human artificial chromosome vector delivery with herpes simplex virus 1 amplicons
نویسندگان
چکیده
منابع مشابه
A novel human artificial chromosome gene expression system using herpes simplex virus type 1 vectors.
Human artificial chromosome (HAC) vectors are an important gene transfer system for expression and complementation studies. We describe a significant advance in HAC technology using infectious herpes simplex virus type 1 (HSV-1) amplicon vectors for delivery. This highly efficient method has allowed gene-expressing HACs to be established in glioma-, kidney- and lung-derived cells. We also devel...
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ژورنال
عنوان ژورنال: Experimental Cell Research
سال: 2020
ISSN: 0014-4827
DOI: 10.1016/j.yexcr.2020.111840